abnormal T cell differentiation_Csk<tm1Sor>/Csk<+>,Ptprc<ltng>/Ptprc<tm1Mak>

http://metadb.riken.jp/0002145I129S7SvEvBrdC57BL6Csktm1SorCskPtprcltngPtprctm1MakPtprctm1MakPtprcltngCskCsktm1Sor

abnormal T cell differentiation_Csk<tm1Sor>/Csk<+>,Ptprc<ltng>/Ptprc<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, receptor type, C
  http://metadb.riken.jp/db/mgi_rdf/MGI:97810
• c-src tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88537

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Csk<tm1Sor>/Csk<+>,Ptprc<ltng>/Ptprc<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptprc<tm1Mak>|Ptprc<ltng>|Csk<+>|Csk<tm1Sor>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell differentiation
  http://purl.obolibrary.org/obo/MP_0002145

文献

http://purl.org/net/cito/citesAsAuthority

• Julie. Zikherman, et.al., CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development., Immunity, 2010, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/20346773