abnormal T cell differentiation_Gata3<tm1Jfz>/Gata3<tm1Jfz>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Cd4-cre)1Cwi/0,Tg(Tcra5CC7,Tcrb5CC7)IWep/0

http://metadb.riken.jp/0002145I129SSvEvC57BL6DBA2Gata3tm1JfzGata3tm1JfzRag2tm1FwaRag2tm1FwaTgCd4cre1Cwi0TgTcra5CC7Tcrb5CC7IWep0Rag2tm1FwaGata3tm1JfzTgTcra5CC7Tcrb5CC7IWepTgCd4cre1Cwi

abnormal T cell differentiation_Gata3<tm1Jfz>/Gata3<tm1Jfz>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Cd4-cre)1Cwi/0,Tg(Tcra5CC7,Tcrb5CC7)IWep/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• GATA binding protein 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95663
• transgene insertion I, William E Paul
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761176
• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gata3<tm1Jfz>/Gata3<tm1Jfz>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Cd4-cre)1Cwi/0,Tg(Tcra5CC7,Tcrb5CC7)IWep/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rag2<tm1Fwa>|Gata3<tm1Jfz>|Tg(Tcra5CC7,Tcrb5CC7)IWep|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell differentiation
  http://purl.obolibrary.org/obo/MP_0002145

文献

http://purl.org/net/cito/citesAsAuthority

• Lie. Wang, et.al., Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18776904