abnormal neural tube morphology_Sox2<tm1.1Knd>/Sox2<tm1.1Knd>,Tbx6<tm1Pa>/Tbx6<tm1Pa>

http://metadb.riken.jp/0002151I129S1Sv129X1SvJC57BL6Sox2tm11KndSox2tm11KndTbx6tm1PaTbx6tm1PaSox2tm11KndTbx6tm1Pa

abnormal neural tube morphology_Sox2<tm1.1Knd>/Sox2<tm1.1Knd>,Tbx6<tm1Pa>/Tbx6<tm1Pa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SRY (sex determining region Y)-box 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:98364
• T-box 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:102539

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sox2<tm1.1Knd>/Sox2<tm1.1Knd>,Tbx6<tm1Pa>/Tbx6<tm1Pa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sox2<tm1.1Knd>|Tbx6<tm1Pa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neural tube morphology/development
  http://purl.obolibrary.org/obo/MP_0002151

文献

http://purl.org/net/cito/citesAsAuthority

• Tatsuya. Takemoto, et.al., Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells., Nature, 2011, 470
  http://rdf.ncbi.nlm.nih.gov/pubmed/21331042