altered tumor susceptibility_Itgb1<tm4Ref>/Itgb1<tm4Ref>,Tg(Ins2-cre)1Heed/?,Tg(RIP1-Tag)2Dh/?

http://metadb.riken.jp/0002166IC57BL6C57BL6JCBADBA2JItgb1tm4RefItgb1tm4RefTgIns2cre1HeedTgRIP1Tag2DhItgb1tm4RefTgIns2cre1HeedTgRIP1Tag2Dh

altered tumor susceptibility_Itgb1<tm4Ref>/Itgb1<tm4Ref>,Tg(Ins2-cre)1Heed/?,Tg(RIP1-Tag)2Dh/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin beta 1 (fibronectin receptor beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96610
• transgene insertion 2, Douglas Hanahan
  http://metadb.riken.jp/db/mgi_rdf/MGI:2429940
• transgene insertion 1, Helena Edlund
  http://metadb.riken.jp/db/mgi_rdf/MGI:3603308

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Itgb1<tm4Ref>/Itgb1<tm4Ref>,Tg(Ins2-cre)1Heed/?,Tg(RIP1-Tag)2Dh/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Itgb1<tm4Ref>|Tg(Ins2-cre)1Heed|Tg(RIP1-Tag)2Dh

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * CBA * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• altered tumor susceptibility
  http://purl.obolibrary.org/obo/MP_0002166

文献

http://purl.org/net/cito/citesAsAuthority

• Angelika. Kren, et.al., Increased tumor cell dissemination and cellular senescence in the absence of beta1-integrin function., The EMBO journal, 2007, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/17541405