decreased brain weight_Sirt2<tm1Gdon>/Sirt2<tm1Gdon>,Tg(HDexon1)62Gpb/0

http://metadb.riken.jp/0002175I129P2OlaHsdC57BL6CBASirt2tm1GdonSirt2tm1GdonTgHDexon162Gpb0TgHDexon162GpbSirt2tm1Gdon

decreased brain weight_Sirt2<tm1Gdon>/Sirt2<tm1Gdon>,Tg(HDexon1)62Gpb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sirtuin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927664
• transgene insertion 62, Gillian Bates
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653601

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sirt2<tm1Gdon>/Sirt2<tm1Gdon>,Tg(HDexon1)62Gpb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(HDexon1)62Gpb|Sirt2<tm1Gdon>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased brain weight
  http://purl.obolibrary.org/obo/MP_0002175

文献

http://purl.org/net/cito/citesAsAuthority

• Anna. Bobrowska, et.al., SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/22511966