decreased brain weight_Bace1<tm1Pcw>/Bace1<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-CDK5R1/GFP)337Lht/0

http://metadb.riken.jp/0002175I129S1Sv129X1SvJC57BL6JBace1tm1PcwBace1TgCamk2atTA1Mmay0TgtetOCDK5R1GFP337Lht0TgCamk2atTA1MmayTgtetOCDK5R1GFP337LhtBace1tm1PcwBace1

decreased brain weight_Bace1<tm1Pcw>/Bace1<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-CDK5R1/GFP)337Lht/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 337, Li-Huei Tsai
  http://metadb.riken.jp/db/mgi_rdf/MGI:3653675
• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062
• beta-site APP cleaving enzyme 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346542

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bace1<tm1Pcw>/Bace1<+>,Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-CDK5R1/GFP)337Lht/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Camk2a-tTA)1Mmay|Tg(tetO-CDK5R1/GFP)337Lht|Bace1<tm1Pcw>|Bace1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased brain weight
  http://purl.obolibrary.org/obo/MP_0002175

文献

http://purl.org/net/cito/citesAsAuthority

• Paola. Giusti-Rodríguez, et.al., Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1)., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/22049418