abnormal innervation_Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm2.1Stl>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Slc6a4-cre)ET127Gsat/0

http://metadb.riken.jp/0002184I129S4SvJae129S6SvEvTacC57BL6FVBNSJLGrin1tm1cEUCOMMWtsiGrin1tm21StlGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgSlc6a4creET127Gsat0GtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorTgSlc6a4creET127GsatGrin1tm1cEUCOMMWtsiGrin1tm21Stl

abnormal innervation_Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm2.1Stl>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Slc6a4-cre)ET127Gsat/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutamate receptor, ionotropic, NMDA1 (zeta 1)
  http://metadb.riken.jp/db/mgi_rdf/MGI:95819
• transgene insertion ET127, GENSAT Project at Rockefeller University
  http://metadb.riken.jp/db/mgi_rdf/MGI:4367072
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grin1<tm1c(EUCOMM)Wtsi>/Grin1<tm2.1Stl>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>,Tg(Slc6a4-cre)ET127Gsat/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>|Gt(ROSA)26Sor<+>|Tg(Slc6a4-cre)ET127Gsat|Grin1<tm1c(EUCOMM)Wtsi>|Grin1<tm2.1Stl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal innervation
  http://purl.obolibrary.org/obo/MP_0002184

文献

http://purl.org/net/cito/citesAsAuthority

• Zhong-wei. Zhang, et.al., Essential role of postsynaptic NMDA receptors in developmental refinement of excitatory synapses., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/23277569