abnormal myocardial trabeculae morphology_Ezh2<tm2Sho>/Ezh2<tm2Sho>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

http://metadb.riken.jp/0002189I129S1Sv129S7SvEvBrdEzh2tm2ShoEzh2tm2ShoNkx25tm1creRjsNkx25Nkx25Nkx25tm1creRjsEzh2tm2Sho

abnormal myocardial trabeculae morphology_Ezh2<tm2Sho>/Ezh2<tm2Sho>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• enhancer of zeste 2 polycomb repressive complex 2 subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:107940
• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ezh2<tm2Sho>/Ezh2<tm2Sho>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nkx2-5<+>|Nkx2-5<tm1(cre)Rjs>|Ezh2<tm2Sho>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal myocardial trabeculae morphology
  http://purl.obolibrary.org/obo/MP_0002189

文献

http://purl.org/net/cito/citesAsAuthority

• Aibin. He, et.al., PRC2 directly methylates GATA4 and represses its transcriptional activity., Genes & development, 2012, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/22215809