neurodegeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-APPSwInd)885Dbo/0,Tg(tetO-LRRK2*G2019S)E3Cai/0

http://metadb.riken.jp/0002229IC3HHeJC57BL6TgCamk2atTA1Mmay0TgtetOAPPSwInd885Dbo0TgtetOLRRK2G2019SE3Cai0TgtetOAPPSwInd885DboTgCamk2atTA1MmayTgtetOLRRK2G2019SE3Cai

neurodegeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-APPSwInd)885Dbo/0,Tg(tetO-LRRK2*G2019S)E3Cai/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062
• transgene insertion 885, David R Borchelt
  http://metadb.riken.jp/db/mgi_rdf/MGI:3696074
• transgene insertion E3, Huaibin Cai
  http://metadb.riken.jp/db/mgi_rdf/MGI:4420754

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-APPSwInd)885Dbo/0,Tg(tetO-LRRK2*G2019S)E3Cai/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-APPSwInd)885Dbo|Tg(Camk2a-tTA)1Mmay|Tg(tetO-LRRK2*G2019S)E3Cai

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H/HeJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• neurodegeneration
  http://purl.obolibrary.org/obo/MP_0002229

文献

http://purl.org/net/cito/citesAsAuthority

• Xian. Lin, et.al., Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein., Neuron, 2009, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/20064389