abnormal bronchiole morphology_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Scgb1a1-cre)1Tauc/0

http://metadb.riken.jp/0002267I129S4SvJaeC57BL6Krastm4TyjKrasPtentm1HwuPtentm1HwuTgScgb1a1cre1Tauc0TgScgb1a1cre1TaucPtentm1HwuKrasKrastm4Tyj

abnormal bronchiole morphology_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Scgb1a1-cre)1Tauc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Michael Tauc
  http://metadb.riken.jp/db/mgi_rdf/MGI:3610309
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Scgb1a1-cre)1Tauc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Scgb1a1-cre)1Tauc|Pten<tm1Hwu>|Kras<+>|Kras<tm4Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal bronchiole morphology
  http://purl.obolibrary.org/obo/MP_0002267

文献

http://purl.org/net/cito/citesAsAuthority

• Yanan. Yang, et.al., Phosphatidylinositol 3-kinase mediates bronchioalveolar stem cell expansion in mouse models of oncogenic K-ras-induced lung cancer., PloS one, 2008, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/18493606