abnormal nervous system electrophysiology_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Chat<tm1(cre)Lowl>/Chat<+>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0002272I129S6SvEvTacC57BL6NCrMc4rtm2LowlMc4rtm2LowlChattm1creLowlChatGtROSA26Sortm14CAGtdTomatoHzeGtROSA26SorGtROSA26SorMc4rtm2LowlGtROSA26Sortm14CAGtdTomatoHzeChatChattm1creLowl

abnormal nervous system electrophysiology_Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Chat<tm1(cre)Lowl>/Chat<+>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• melanocortin 4 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:99457
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• choline acetyltransferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88392

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mc4r<tm2Lowl>/Mc4r<tm2Lowl>,Chat<tm1(cre)Lowl>/Chat<+>,Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Mc4r<tm2Lowl>|Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>|Chat<+>|Chat<tm1(cre)Lowl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6NCr

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal nervous system electrophysiology
  http://purl.obolibrary.org/obo/MP_0002272

文献

http://purl.org/net/cito/citesAsAuthority

• Jong-Woo. Sohn, et.al., Melanocortin 4 receptors reciprocally regulate sympathetic and parasympathetic preganglionic neurons., Cell, 2013, 152
  http://rdf.ncbi.nlm.nih.gov/pubmed/23374353