abnormal nervous system electrophysiology_Tg(Prnp-HSPB1*R136W)1Kolb/0

http://metadb.riken.jp/0002272IFVBNJTgPrnpHSPB1R136W1Kolb0TgPrnpHSPB1R136W1Kolb

abnormal nervous system electrophysiology_Tg(Prnp-HSPB1*R136W)1Kolb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Stephen Kolb
  http://metadb.riken.jp/db/mgi_rdf/MGI:5440461

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-HSPB1*R136W)1Kolb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-HSPB1*R136W)1Kolb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/NJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal nervous system electrophysiology
  http://purl.obolibrary.org/obo/MP_0002272

文献

http://purl.org/net/cito/citesAsAuthority

• Amit K. Srivastava, et.al., Mutant HSPB1 overexpression in neurons is sufficient to cause age-related motor neuronopathy in mice., Neurobiology of disease, 2012, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/22521462