abnormal type II pneumocyte morphology_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0

http://metadb.riken.jp/0002275I129129S1Sv129X1SvJC57BL6Hif1atm3RsjoHif1atm3RsjoTgSFTPCrtTA5Jaw0TgtetOcre1Jaw0Hif1atm3RsjoTgtetOcre1JawTgSFTPCrtTA5Jaw

abnormal type II pneumocyte morphology_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028584
• transgene insertion 5, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679530
• hypoxia inducible factor 1, alpha subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:106918

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Tg(SFTPC-rtTA)5Jaw/0,Tg(tetO-cre)1Jaw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hif1a<tm3Rsjo>|Tg(tetO-cre)1Jaw|Tg(SFTPC-rtTA)5Jaw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal type II pneumocyte morphology
  http://purl.obolibrary.org/obo/MP_0002275

文献

http://purl.org/net/cito/citesAsAuthority

• Yogesh. Saini, et.al., HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18801745