abnormal respiratory mucosa goblet cell morphology_Sox2<tm1.1Lan>/Sox2<tm1.1Lan>,Tg(Scgb1a1-cre)1Kkw/0

http://metadb.riken.jp/0002281I129SvC57BL6Sox2tm11LanSox2tm11LanTgScgb1a1cre1Kkw0TgScgb1a1cre1KkwSox2tm11Lan

abnormal respiratory mucosa goblet cell morphology_Sox2<tm1.1Lan>/Sox2<tm1.1Lan>,Tg(Scgb1a1-cre)1Kkw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SRY (sex determining region Y)-box 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:98364
• transgene insertion 1, K Wong
  http://metadb.riken.jp/db/mgi_rdf/MGI:3623211

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sox2<tm1.1Lan>/Sox2<tm1.1Lan>,Tg(Scgb1a1-cre)1Kkw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Scgb1a1-cre)1Kkw|Sox2<tm1.1Lan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal respiratory mucosa goblet cell morphology
  http://purl.obolibrary.org/obo/MP_0002281

文献

http://purl.org/net/cito/citesAsAuthority

• David H. Tompkins, et.al., Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/20011520