abnormal spleen germinal center morphology_Igh-J<tm1Mcdl>/Igh-J<tm1Mcdl>,Igk-J<tm1Mcdl>/Igk-J<tm1Mcdl>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(DO11.10)10Dlo/?

http://metadb.riken.jp/0002359I129S4SvJae129S7SvEvBrdBALBcIghJtm1McdlIghJtm1McdlIgkJtm1McdlIgkJtm1McdlRag1tm1MomRag1tm1MomTgDO111010DloIgkJtm1McdlTgDO111010DloIghJtm1McdlRag1tm1Mom

abnormal spleen germinal center morphology_Igh-J<tm1Mcdl>/Igh-J<tm1Mcdl>,Igk-J<tm1Mcdl>/Igk-J<tm1Mcdl>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(DO11.10)10Dlo/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97848
• immunoglobulin kappa chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96497
• transgene insertion 10, Dennis Y Loh
  http://metadb.riken.jp/db/mgi_rdf/MGI:2664401
• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-J<tm1Mcdl>/Igh-J<tm1Mcdl>,Igk-J<tm1Mcdl>/Igk-J<tm1Mcdl>,Rag1<tm1Mom>/Rag1<tm1Mom>,Tg(DO11.10)10Dlo/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igk-J<tm1Mcdl>|Tg(DO11.10)10Dlo|Igh-J<tm1Mcdl>|Rag1<tm1Mom>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S7/SvEvBrd * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal spleen germinal center morphology
  http://purl.obolibrary.org/obo/MP_0002359

文献

http://purl.org/net/cito/citesAsAuthority

• M A. Curotto de Lafaille, et.al., Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes., The Journal of experimental medicine, 2001, 194
  http://rdf.ncbi.nlm.nih.gov/pubmed/11696599