abnormal hematopoietic system morphology/development_Mre11a<tm1Jpt>/Mre11a<+>,Rad50<tm2Jpt>/Rad50<tm2Jpt>

http://metadb.riken.jp/0002396I129S7SvEvBrdC57BL6Mre11atm1JptMre11aRad50tm2JptRad50tm2JptMre11aMre11atm1JptRad50tm2Jpt

abnormal hematopoietic system morphology/development_Mre11a<tm1Jpt>/Mre11a<+>,Rad50<tm2Jpt>/Rad50<tm2Jpt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• MRE11A homolog A, double strand break repair nuclease
  http://metadb.riken.jp/db/mgi_rdf/MGI:1100512
• RAD50 double strand break repair protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:109292

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mre11a<tm1Jpt>/Mre11a<+>,Rad50<tm2Jpt>/Rad50<tm2Jpt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mre11a<+>|Mre11a<tm1Jpt>|Rad50<tm2Jpt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal hematopoietic system morphology/development
  http://purl.obolibrary.org/obo/MP_0002396

文献

http://purl.org/net/cito/citesAsAuthority

• Monica. Morales, et.al., The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor., Genes & development, 2005, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/16357220