increased intestinal adenoma incidence_Apc<tm1Rak>/Apc<+>,Smad4<E6sad>/Smad4<+>

http://metadb.riken.jp/0002404B6129P2Apctm1RakSmad4E6sadApctm1RakApcSmad4E6sadSmad4Apctm1RakSmad4E6sadApcSmad4

increased intestinal adenoma incidence_Apc<tm1Rak>/Apc<+>,Smad4<E6sad>/Smad4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SMAD family member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:894293
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm1Rak>/Apc<+>,Smad4<E6sad>/Smad4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<tm1Rak>|Smad4<E6sad>|Apc<+>|Smad4<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129P2-Apc<tm1Rak> +/+ Smad4<E6sad>
• B6.129P2-Apc<tm1Rak> Smad4<E6sad>/+ +

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002404

文献

http://purl.org/net/cito/citesAsAuthority

• P. Alberici, et.al., Smad4 haploinsufficiency in mouse models for intestinal cancer., Oncogene, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16288217