increased intestinal adenoma incidence_Apc<tm1Mmt>/Apc<+>,Smad2<tm2Kato>/Smad2<+>

http://metadb.riken.jp/0002404I129S2SvPas129S4SvJaeC57BL6JApctm1MmtApcSmad2tm2KatoSmad2Smad2ApcApctm1MmtSmad2tm2Kato

increased intestinal adenoma incidence_Apc<tm1Mmt>/Apc<+>,Smad2<tm2Kato>/Smad2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SMAD family member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:108051
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm1Mmt>/Apc<+>,Smad2<tm2Kato>/Smad2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smad2<+>|Apc<+>|Apc<tm1Mmt>|Smad2<tm2Kato>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002404

文献

http://purl.org/net/cito/citesAsAuthority

• Toshiaki. Hamamoto, et.al., Compound disruption of smad2 accelerates malignant progression of intestinal tumors in apc knockout mice., Cancer research, 2002, 62
  http://rdf.ncbi.nlm.nih.gov/pubmed/12384562