increased intestinal adenoma incidence_Apc<Min>/Apc<+>,Ccnd1<tm1Dsn>/Ccnd1<tm1Dsn>

http://metadb.riken.jp/0002404IC57BL6JApcMinApcCcnd1tm1DsnCcnd1tm1DsnCcnd1tm1DsnApcApcMin

increased intestinal adenoma incidence_Apc<Min>/Apc<+>,Ccnd1<tm1Dsn>/Ccnd1<tm1Dsn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• cyclin D1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88313

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<Min>/Apc<+>,Ccnd1<tm1Dsn>/Ccnd1<tm1Dsn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ccnd1<tm1Dsn>|Apc<+>|Apc<Min>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased intestinal adenoma incidence
  http://purl.obolibrary.org/obo/MP_0002404

文献

http://purl.org/net/cito/citesAsAuthority

• Jenny. Wilding, et.al., Cyclin D1 is not an essential target of beta-catenin signaling during intestinal tumorigenesis, but it may act as a modifier of disease severity in multiple intestinal neoplasia (Min) mice., Cancer research, 2002, 62
  http://rdf.ncbi.nlm.nih.gov/pubmed/12183406