increased susceptibility to infection_Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>

http://metadb.riken.jp/0002406E129S6SvEvTacorI129S6SvEvTacC57BL6Sh2d1atm1PlsSh2d1atm1PlsSh2d1atm1Pls

increased susceptibility to infection_Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SH2 domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328352

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2d1a<tm1Pls>/Sh2d1a<tm1Pls>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sh2d1a<tm1Pls>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to infection
  http://purl.obolibrary.org/obo/MP_0002406

文献

http://purl.org/net/cito/citesAsAuthority

• M J. Czar, et.al., Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11404475