decreased susceptibility to viral infection_Ccr5<tm1Kuz>/Ccr5<tm1Kuz>,Cxcr4<tm1Qma>/Cxcr4<tm1Qma>

http://metadb.riken.jp/0002410I129P2OlaHsd129X1SvJC57BL6Ccr5tm1KuzCcr5tm1KuzCxcr4tm1QmaCxcr4tm1QmaCxcr4tm1QmaCcr5tm1Kuz

decreased susceptibility to viral infection_Ccr5<tm1Kuz>/Ccr5<tm1Kuz>,Cxcr4<tm1Qma>/Cxcr4<tm1Qma>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chemokine (C-C motif) receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:107182
• chemokine (C-X-C motif) receptor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:109563

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccr5<tm1Kuz>/Ccr5<tm1Kuz>,Cxcr4<tm1Qma>/Cxcr4<tm1Qma>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cxcr4<tm1Qma>|Ccr5<tm1Kuz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to viral infection
  http://purl.obolibrary.org/obo/MP_0002410

文献

http://purl.org/net/cito/citesAsAuthority

• M. Kaul, et.al., HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection., Cell death and differentiation, 2007, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/16841089