decreased susceptibility to viral infection_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Nefh-cre)22Jcol/?,Tg(Prnp)46Jcol/?

http://metadb.riken.jp/0002410I129Sv129S7SvEvBrdC57BL6FVBPrnptm1CwePrnptm1CweTgNefhcre22JcolTgPrnp46JcolTgNefhcre22JcolPrnptm1CweTgPrnp46Jcol

decreased susceptibility to viral infection_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Nefh-cre)22Jcol/?,Tg(Prnp)46Jcol/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 46, John Collinge
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761839
• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769
• transgene insertion 22, John Collinge
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761835

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Nefh-cre)22Jcol/?,Tg(Prnp)46Jcol/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nefh-cre)22Jcol|Prnp<tm1Cwe>|Tg(Prnp)46Jcol

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S7/SvEvBrd * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to viral infection
  http://purl.obolibrary.org/obo/MP_0002410

文献

http://purl.org/net/cito/citesAsAuthority

• G R. Mallucci, et.al., Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration., The EMBO journal, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/11823413