increased susceptibility to bacterial infection_Il18<tm1Aki>/Il18<tm1Aki>,Il1b<tm1Dch>/Il1b<tm1Dch>

http://metadb.riken.jp/0002412I129P2OlaHsd129S2SvPasIl18tm1AkiIl18tm1AkiIl1btm1DchIl1btm1DchIl18tm1AkiIl1btm1Dch

increased susceptibility to bacterial infection_Il18<tm1Aki>/Il18<tm1Aki>,Il1b<tm1Dch>/Il1b<tm1Dch>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interleukin 18
  http://metadb.riken.jp/db/mgi_rdf/MGI:107936
• interleukin 1 beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:96543

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il18<tm1Aki>/Il18<tm1Aki>,Il1b<tm1Dch>/Il1b<tm1Dch>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il18<tm1Aki>|Il1b<tm1Dch>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to bacterial infection
  http://purl.obolibrary.org/obo/MP_0002412

文献

http://purl.org/net/cito/citesAsAuthority

• Bärbel. Raupach, et.al., Caspase-1-mediated activation of interleukin-1beta (IL-1beta) and IL-18 contributes to innate immune defenses against Salmonella enterica serovar Typhimurium infection., Infection and immunity, 2006, 74
  http://rdf.ncbi.nlm.nih.gov/pubmed/16861683