increased susceptibility to bacterial infection_C3<tm1Crr>/C3<tm1Crr>

http://metadb.riken.jp/0002412I129S4SvJaeC57BL6C3tm1CrrC3tm1CrrC3tm1Crr

increased susceptibility to bacterial infection_C3<tm1Crr>/C3<tm1Crr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• complement component 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:88227

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• C3<tm1Crr>/C3<tm1Crr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• C3<tm1Crr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to bacterial infection
  http://purl.obolibrary.org/obo/MP_0002412

文献

http://purl.org/net/cito/citesAsAuthority

• A P. Prodeus, et.al., Impaired mast cell-dependent natural immunity in complement C3-deficient mice., Nature, 1997, 390
  http://rdf.ncbi.nlm.nih.gov/pubmed/9367154
• M R. Wessels, et.al., Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/8524789