abnormal megakaryocyte progenitor cell morphology_Ep300<Plt6>/Ep300<+>,Mpl<tm1Wsa>/Mpl<tm1Wsa>

http://metadb.riken.jp/0002413I129S1SvC57BL6Ep300Plt6Ep300Mpltm1WsaMpltm1WsaEp300Mpltm1WsaEp300Plt6

abnormal megakaryocyte progenitor cell morphology_Ep300<Plt6>/Ep300<+>,Mpl<tm1Wsa>/Mpl<tm1Wsa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• E1A binding protein p300
  http://metadb.riken.jp/db/mgi_rdf/MGI:1276116
• myeloproliferative leukemia virus oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97076

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ep300<Plt6>/Ep300<+>,Mpl<tm1Wsa>/Mpl<tm1Wsa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ep300<+>|Mpl<tm1Wsa>|Ep300<Plt6>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal megakaryocyte progenitor cell morphology
  http://purl.obolibrary.org/obo/MP_0002413

文献

http://purl.org/net/cito/citesAsAuthority

• Maria. Kauppi, et.al., Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice., Blood, 2008, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/18684867