increased susceptibility to viral infection_Tyk2<tm1Biat>/Tyk2<tm1Biat>

http://metadb.riken.jp/0002418I129P2OlaHsdC57BL6Tyk2tm1BiatTyk2tm1BiatTyk2tm1Biat

increased susceptibility to viral infection_Tyk2<tm1Biat>/Tyk2<tm1Biat>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tyrosine kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929470

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tyk2<tm1Biat>/Tyk2<tm1Biat>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tyk2<tm1Biat>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to viral infection
  http://purl.obolibrary.org/obo/MP_0002418

文献

http://purl.org/net/cito/citesAsAuthority

• M. Karaghiosoff, et.al., Partial impairment of cytokine responses in Tyk2-deficient mice., Immunity, 2000, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/11070173
• Birgit. Strobl, et.al., Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus., Journal of immunology (Baltimore, Md. : 1950), 2005, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/16148148