increased susceptibility to viral infection_Eif2ak2<tm1Jcbe>/Eif2ak2<tm1Jcbe>

http://metadb.riken.jp/0002418I129S4SvJaeEif2ak2tm1JcbeEif2ak2tm1JcbeEif2ak2tm1Jcbe

increased susceptibility to viral infection_Eif2ak2<tm1Jcbe>/Eif2ak2<tm1Jcbe>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• eukaryotic translation initiation factor 2-alpha kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1353449

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Eif2ak2<tm1Jcbe>/Eif2ak2<tm1Jcbe>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Eif2ak2<tm1Jcbe>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to viral infection
  http://purl.obolibrary.org/obo/MP_0002418

文献

http://purl.org/net/cito/citesAsAuthority

• Ai. Harashima, et.al., Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense., Genes & development, 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/21123651
• S. Balachandran, et.al., Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection., Immunity, 2000, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/10933401