abnormal mast cell physiology_Nf1<tm1Tyj>/Nf1<+>,Pak1<tm1Cher>/Pak1<tm1Cher>

http://metadb.riken.jp/0002423I129S2SvPasC57BL6Nf1tm1TyjNf1Pak1tm1CherPak1tm1CherPak1tm1CherNf1Nf1tm1Tyj

abnormal mast cell physiology_Nf1<tm1Tyj>/Nf1<+>,Pak1<tm1Cher>/Pak1<tm1Cher>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• p21 protein (Cdc42/Rac)-activated kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1339975
• neurofibromin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97306

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf1<tm1Tyj>/Nf1<+>,Pak1<tm1Cher>/Pak1<tm1Cher>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pak1<tm1Cher>|Nf1<+>|Nf1<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal mast cell physiology
  http://purl.obolibrary.org/obo/MP_0002423

文献

http://purl.org/net/cito/citesAsAuthority

• Andrew S. McDaniel, et.al., Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells., Blood, 2008, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/18768391