abnormal blood cell morphology/development_Kras<tm4Tyj>/Kras<+>,Lrrc17<tm1Nik>/Lrrc17<+>,Srpk2<tm1Nik>/Srpk2<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0002429I129P2OlaHsd129S4SvJaeC57BL6CBAKrastm4TyjKrasLrrc17tm1NikLrrc17Srpk2tm1NikSrpk2TgMx1cre1Cgn0Krastm4TyjSrpk2tm1NikLrrc17tm1NikKrasTgMx1cre1CgnLrrc17Srpk2

abnormal blood cell morphology/development_Kras<tm4Tyj>/Kras<+>,Lrrc17<tm1Nik>/Lrrc17<+>,Srpk2<tm1Nik>/Srpk2<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• serine/arginine-rich protein specific kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1201408
• leucine rich repeat containing 17
  http://metadb.riken.jp/db/mgi_rdf/MGI:1921761
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Lrrc17<tm1Nik>/Lrrc17<+>,Srpk2<tm1Nik>/Srpk2<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm4Tyj>|Srpk2<tm1Nik>|Lrrc17<tm1Nik>|Kras<+>|Tg(Mx1-cre)1Cgn|Lrrc17<+>|Srpk2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal blood cell morphology/development
  http://purl.obolibrary.org/obo/MP_0002429

文献

http://purl.org/net/cito/citesAsAuthority

• Jasmine C Y. Wong, et.al., Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies., Blood, 2010, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/20233966