abnormal CD8-positive, alpha-beta cytotoxic T cell morphology_Gzmb<tm1Ley>/Gzmb<tm1Ley>,Serpinb9<tm1Arp>/Serpinb9<tm1Arp>

http://metadb.riken.jp/0002436I129S2SvPasC57BL6Gzmbtm1LeyGzmbtm1LeySerpinb9tm1ArpSerpinb9tm1ArpGzmbtm1LeySerpinb9tm1Arp

abnormal CD8-positive, alpha-beta cytotoxic T cell morphology_Gzmb<tm1Ley>/Gzmb<tm1Ley>,Serpinb9<tm1Arp>/Serpinb9<tm1Arp>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• granzyme B
  http://metadb.riken.jp/db/mgi_rdf/MGI:109267
• serine (or cysteine) peptidase inhibitor, clade B, member 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:106603

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gzmb<tm1Ley>/Gzmb<tm1Ley>,Serpinb9<tm1Arp>/Serpinb9<tm1Arp>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gzmb<tm1Ley>|Serpinb9<tm1Arp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal CD8-positive, alpha-beta cytotoxic T cell morphology
  http://purl.obolibrary.org/obo/MP_0002436

文献

http://purl.org/net/cito/citesAsAuthority

• Manling. Zhang, et.al., Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules., Immunity, 2006, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/16618603