abnormal leukocyte physiology_Gzma<tm1Simn>/Gzma<tm1Simn>,Gzmb<tm1Ley>/Gzmb<tm1Ley>

http://metadb.riken.jp/0002442I129S2SvPasC57BL6Gzmatm1SimnGzmatm1SimnGzmbtm1LeyGzmbtm1LeyGzmatm1SimnGzmbtm1Ley

abnormal leukocyte physiology_Gzma<tm1Simn>/Gzma<tm1Simn>,Gzmb<tm1Ley>/Gzmb<tm1Ley>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• granzyme B
  http://metadb.riken.jp/db/mgi_rdf/MGI:109267
• granzyme A
  http://metadb.riken.jp/db/mgi_rdf/MGI:109266

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gzma<tm1Simn>/Gzma<tm1Simn>,Gzmb<tm1Ley>/Gzmb<tm1Ley>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gzma<tm1Simn>|Gzmb<tm1Ley>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal leukocyte physiology
  http://purl.obolibrary.org/obo/MP_0002442

文献

http://purl.org/net/cito/citesAsAuthority

• M M. Simon, et.al., In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells., The Journal of experimental medicine, 1997, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/9362539