abnormal T cell physiology_Cblb<tm1Pngr>/Cblb<tm1Pngr>,Vav1<tm1Tyb>/Vav1<tm1Tyb>,Was<tm1Sbs>/Was<tm1Sbs>

http://metadb.riken.jp/0002444I129P2OlaHsd129S2SvPas129S6SvEvTacCblbtm1PngrCblbtm1PngrVav1tm1TybVav1tm1TybWastm1SbsWastm1SbsWastm1SbsVav1tm1TybCblbtm1Pngr

abnormal T cell physiology_Cblb<tm1Pngr>/Cblb<tm1Pngr>,Vav1<tm1Tyb>/Vav1<tm1Tyb>,Was<tm1Sbs>/Was<tm1Sbs>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923
• Wiskott-Aldrich syndrome
  http://metadb.riken.jp/db/mgi_rdf/MGI:105059
• Casitas B-lineage lymphoma b
  http://metadb.riken.jp/db/mgi_rdf/MGI:2146430

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cblb<tm1Pngr>/Cblb<tm1Pngr>,Vav1<tm1Tyb>/Vav1<tm1Tyb>,Was<tm1Sbs>/Was<tm1Sbs>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Was<tm1Sbs>|Vav1<tm1Tyb>|Cblb<tm1Pngr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal T cell physiology
  http://purl.obolibrary.org/obo/MP_0002444

文献

http://purl.org/net/cito/citesAsAuthority

• C. Krawczyk, et.al., Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells., Immunity, 2000, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/11070165