abnormal macrophage physiology_Apoe<tm1Unc>/Apoe<tm1Unc>,Nfe2l2<tm1Mym>/Nfe2l2<tm1Mym>

http://metadb.riken.jp/0002451I129P2OlaHsdC57BL6JApoetm1UncApoetm1UncNfe2l2tm1MymNfe2l2tm1MymApoetm1UncNfe2l2tm1Mym

abnormal macrophage physiology_Apoe<tm1Unc>/Apoe<tm1Unc>,Nfe2l2<tm1Mym>/Nfe2l2<tm1Mym>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear factor, erythroid derived 2, like 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:108420
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Nfe2l2<tm1Mym>/Nfe2l2<tm1Mym>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apoe<tm1Unc>|Nfe2l2<tm1Mym>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal macrophage physiology
  http://purl.obolibrary.org/obo/MP_0002451

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas E. Sussan, et.al., Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice., PloS one, 2008, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/19023427