abnormal macrophage physiology_Fgr<tm1Hev>/Fgr<tm1Hev>,Hck<tm1Hev>/Hck<tm1Hev>

http://metadb.riken.jp/0002451I129S7SvEvBrdC57BL6JFgrtm1HevFgrtm1HevHcktm1HevHcktm1HevHcktm1HevFgrtm1Hev

abnormal macrophage physiology_Fgr<tm1Hev>/Fgr<tm1Hev>,Hck<tm1Hev>/Hck<tm1Hev>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FGR proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:95527
• hemopoietic cell kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96052

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgr<tm1Hev>/Fgr<tm1Hev>,Hck<tm1Hev>/Hck<tm1Hev>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hck<tm1Hev>|Fgr<tm1Hev>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal macrophage physiology
  http://purl.obolibrary.org/obo/MP_0002451

文献

http://purl.org/net/cito/citesAsAuthority

• P W. Suen, et.al., Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages., Journal of cell science, 1999, 112 ( Pt 22)
  http://rdf.ncbi.nlm.nih.gov/pubmed/10547366