abnormal macrophage physiology_Nlrp3<tm1Hhf>/Nlrp3<+>,Tg(CAG-cre/Esr1*)5Amc/?

http://metadb.riken.jp/0002451I129SvC57BL6CBANlrp3tm1HhfNlrp3TgCAGcreEsr15AmcTgCAGcreEsr15AmcNlrp3Nlrp3tm1Hhf

abnormal macrophage physiology_Nlrp3<tm1Hhf>/Nlrp3<+>,Tg(CAG-cre/Esr1*)5Amc/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765
• NLR family, pyrin domain containing 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:2653833

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nlrp3<tm1Hhf>/Nlrp3<+>,Tg(CAG-cre/Esr1*)5Amc/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cre/Esr1*)5Amc|Nlrp3<+>|Nlrp3<tm1Hhf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal macrophage physiology
  http://purl.obolibrary.org/obo/MP_0002451

文献

http://purl.org/net/cito/citesAsAuthority

• Susannah D. Brydges, et.al., Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity., Immunity, 2009, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/19501000