abnormal B cell physiology_Igh<tm2Cgn>/Igh<+>,Igk-Eik<tm1Cgn>/Igk-Eik<tm1Cgn>,Arhgef1<tm1.1Rmt>/Arhgef1<tm1.1Rmt>

http://metadb.riken.jp/0002459I129P2OlaHsdC57BL6Ightm2CgnIghIgkEiktm1CgnIgkEiktm1CgnArhgef1tm11RmtArhgef1tm11RmtArhgef1tm11RmtIgkEiktm1CgnIghtm2CgnIgh

abnormal B cell physiology_Igh<tm2Cgn>/Igh<+>,Igk-Eik<tm1Cgn>/Igk-Eik<tm1Cgn>,Arhgef1<tm1.1Rmt>/Arhgef1<tm1.1Rmt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Rho guanine nucleotide exchange factor (GEF) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1353510
• immunoglobulin kappa chain, enhancer intronic
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354193
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm2Cgn>/Igh<+>,Igk-Eik<tm1Cgn>/Igk-Eik<tm1Cgn>,Arhgef1<tm1.1Rmt>/Arhgef1<tm1.1Rmt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Arhgef1<tm1.1Rmt>|Igk-Eik<tm1Cgn>|Igh<tm2Cgn>|Igh<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal B cell physiology
  http://purl.obolibrary.org/obo/MP_0002459

文献

http://purl.org/net/cito/citesAsAuthority

• Anatoly. Rubtsov, et.al., Lsc regulates marginal-zone B cell migration and adhesion and is required for the IgM T-dependent antibody response., Immunity, 2005, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/16286020