increased IgM level_Aicda<tm1Hon>/Aicda<tm1Hon>

http://metadb.riken.jp/0002494IC57BL6CBAAicdatm1HonAicdatm1HonAicdatm1Hon

increased IgM level_Aicda<tm1Hon>/Aicda<tm1Hon>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1Hon>/Aicda<tm1Hon>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Aicda<tm1Hon>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased IgM level
  http://purl.obolibrary.org/obo/MP_0002494

文献

http://purl.org/net/cito/citesAsAuthority

• M. Muramatsu, et.al., Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme., Cell, 2000, 102
  http://rdf.ncbi.nlm.nih.gov/pubmed/11007474
• Min. Wei, et.al., Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense., Nature immunology, 2011, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/21258321