impaired ability to fire action potentials_Nfasc<tm1.1Brp>/Nfasc<tm1.2Brp>,Tg(Thy1-cre/ERT2)#Brp/0

http://metadb.riken.jp/0002578I129P2OlaHsdC57BL6Nfasctm11BrpNfasctm12BrpTgThy1creERT2Brp0Nfasctm12BrpNfasctm11BrpTgThy1creERT2Brp

impaired ability to fire action potentials_Nfasc<tm1.1Brp>/Nfasc<tm1.2Brp>,Tg(Thy1-cre/ERT2)#Brp/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Peter J Brophy
  http://metadb.riken.jp/db/mgi_rdf/MGI:5141309
• neurofascin
  http://metadb.riken.jp/db/mgi_rdf/MGI:104753

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nfasc<tm1.1Brp>/Nfasc<tm1.2Brp>,Tg(Thy1-cre/ERT2)#Brp/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nfasc<tm1.2Brp>|Nfasc<tm1.1Brp>|Tg(Thy1-cre/ERT2)#Brp

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired ability to fire action potentials
  http://purl.obolibrary.org/obo/MP_0002578

文献

http://purl.org/net/cito/citesAsAuthority

• Barbara. Zonta, et.al., A critical role for Neurofascin in regulating action potential initiation through maintenance of the axon initial segment., Neuron, 2011, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/21382554