decreased mean corpuscular volume_Ahsp<tm1Mjwe>/Ahsp<tm1Mjwe>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>

http://metadb.riken.jp/0002591I129P2OlaHsd129S6SvEvTacC57BL6Ahsptm1MjweAhsptm1MjweHbbb1tm1UncHbbb1Hbbb2tm1UncHbbb2Hbbb2Hbbb2tm1UncHbbb1tm1UncAhsptm1MjweHbbb1

decreased mean corpuscular volume_Ahsp<tm1Mjwe>/Ahsp<tm1Mjwe>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hemoglobin, beta adult major chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:96021
• alpha hemoglobin stabilizing protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2158492
• hemoglobin, beta adult minor chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:96022

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ahsp<tm1Mjwe>/Ahsp<tm1Mjwe>,Hbb-b1<tm1Unc>/Hbb-b1<+>,Hbb-b2<tm1Unc>/Hbb-b2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hbb-b2<+>|Hbb-b2<tm1Unc>|Hbb-b1<tm1Unc>|Ahsp<tm1Mjwe>|Hbb-b1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mean corpuscular volume
  http://purl.obolibrary.org/obo/MP_0002591

文献

http://purl.org/net/cito/citesAsAuthority

• Yi. Kong, et.al., Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia., The Journal of clinical investigation, 2004, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/15545996