abnormal lymphocyte morphology_Gt(ROSA)26Sor<em1(Kdelr1)Btlr>/Gt(ROSA)26Sor<+>,Kdelr1<em1Btlr>/Kdelr1<em1Btlr>

http://metadb.riken.jp/0002619C57BL6JGtROSA26Sorem1Kdelr1BtlrKdelr1em1BtlrGtROSA26Sorem1Kdelr1BtlrGtROSA26SorKdelr1em1BtlrKdelr1em1BtlrKdelr1em1BtlrGtROSA26Sorem1Kdelr1BtlrGtROSA26Sor

abnormal lymphocyte morphology_Gt(ROSA)26Sor<em1(Kdelr1)Btlr>/Gt(ROSA)26Sor<+>,Kdelr1<em1Btlr>/Kdelr1<em1Btlr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915387

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<em1(Kdelr1)Btlr>/Gt(ROSA)26Sor<+>,Kdelr1<em1Btlr>/Kdelr1<em1Btlr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kdelr1<em1Btlr>|Gt(ROSA)26Sor<em1(Kdelr1)Btlr>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C57BL/6J-Gt(ROSA)26Sor<em1(Kdelr1)Btlr> Kdelr1<em1Btlr>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lymphocyte morphology
  http://purl.obolibrary.org/obo/MP_0002619

文献

http://purl.org/net/cito/citesAsAuthority

• Owen M. Siggs, et.al., Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection., Proceedings of the National Academy of Sciences of the United States of America, 2015, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/26438836