increased heart rate_Tg(Myh6-Adra1a)A1A1Rmgr/0

http://metadb.riken.jp/0002626FVBNTgMyh6Adra1aA1A1RmgrTgMyh6Adra1aA1A1Rmgr0TgMyh6Adra1aA1A1Rmgr

increased heart rate_Tg(Myh6-Adra1a)A1A1Rmgr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion A1A1, Robert M Graham
  http://metadb.riken.jp/db/mgi_rdf/MGI:3689078

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Myh6-Adra1a)A1A1Rmgr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-Adra1a)A1A1Rmgr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB/N-Tg(Myh6-Adra1a)A1A1Rmgr

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased heart rate
  http://purl.obolibrary.org/obo/MP_0002626

文献

http://purl.org/net/cito/citesAsAuthority

• F. Lin, et.al., Targeted alpha(1A)-adrenergic receptor overexpression induces enhanced cardiac contractility but not hypertrophy., Circulation research, 2001, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/11509451
• H. Chaulet, et.al., Sustained augmentation of cardiac alpha1A-adrenergic drive results in pathological remodeling with contractile dysfunction, progressive fibrosis and reactivation of matricellular protein genes., Journal of molecular and cellular cardiology, 2006, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/16516910