decreased intestinal cholesterol absorption_Soat2<tm1.1Llr>/Soat2<tm1.1Llr>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0002647I129SSvEv129S4SvJaeSorC57BL6JSJLSoat2tm11LlrSoat2tm11LlrTgVil1cre997Gum0TgVil1cre997GumSoat2tm11Llr

decreased intestinal cholesterol absorption_Soat2<tm1.1Llr>/Soat2<tm1.1Llr>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957
• sterol O-acyltransferase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1332226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Soat2<tm1.1Llr>/Soat2<tm1.1Llr>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil1-cre)997Gum|Soat2<tm1.1Llr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased intestinal cholesterol absorption
  http://purl.obolibrary.org/obo/MP_0002647

文献

http://purl.org/net/cito/citesAsAuthority

• Jun. Zhang, et.al., Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood., Journal of lipid research, 2012, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/22460046