decreased intestinal cholesterol absorption_Hsd3b7<tm1Rus>/Hsd3b7<tm1Rus>

http://metadb.riken.jp/0002647I129SSvEvC57BL6JHsd3b7tm1RusHsd3b7tm1RusHsd3b7tm1Rus

decreased intestinal cholesterol absorption_Hsd3b7<tm1Rus>/Hsd3b7<tm1Rus>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:2141879

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hsd3b7<tm1Rus>/Hsd3b7<tm1Rus>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hsd3b7<tm1Rus>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased intestinal cholesterol absorption
  http://purl.obolibrary.org/obo/MP_0002647

文献

http://purl.org/net/cito/citesAsAuthority

• Heidi C. Shea, et.al., Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid function., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17601774