decreased intestinal cholesterol absorption_Tg(ABCG5/ABCG8)14-2Hobb/0

http://metadb.riken.jp/0002647IC57BL6JSJLTgABCG5ABCG8142Hobb0TgABCG5ABCG8142Hobb

decreased intestinal cholesterol absorption_Tg(ABCG5/ABCG8)14-2Hobb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 14-2, Helen H Hobbs
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446955

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(ABCG5/ABCG8)14-2Hobb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(ABCG5/ABCG8)14-2Hobb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased intestinal cholesterol absorption
  http://purl.obolibrary.org/obo/MP_0002647

文献

http://purl.org/net/cito/citesAsAuthority

• Liqing. Yu, et.al., Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol., The Journal of clinical investigation, 2002, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/12208868
• Silvia. Langheim, et.al., ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile., Journal of lipid research, 2005, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/15930516