thin myocardium_Meox2<tm1(cre)Sor>/Meox2<+>,Ptpn11<tm6Bgn>/Ptpn11<+>

http://metadb.riken.jp/0002652I129S4SvJaeSor129S6SvEvTacC57BL6Meox2tm1creSorMeox2Ptpn11tm6BgnPtpn11Meox2tm1creSorPtpn11tm6BgnPtpn11Meox2

thin myocardium_Meox2<tm1(cre)Sor>/Meox2<+>,Ptpn11<tm6Bgn>/Ptpn11<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mesenchyme homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:103219
• protein tyrosine phosphatase, non-receptor type 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:99511

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Meox2<tm1(cre)Sor>/Meox2<+>,Ptpn11<tm6Bgn>/Ptpn11<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Meox2<tm1(cre)Sor>|Ptpn11<tm6Bgn>|Ptpn11<+>|Meox2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• thin myocardium
  http://purl.obolibrary.org/obo/MP_0002652

文献

http://purl.org/net/cito/citesAsAuthority

• Toshiyuki. Araki, et.al., Noonan syndrome cardiac defects are caused by PTPN11 acting in endocardium to enhance endocardial-mesenchymal transformation., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19251646