spongiform encephalopathy_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*P101L)2866Sbp/Tg(Prnp*P101L)2866Sbp

http://metadb.riken.jp/0002654I129S7SvEvBrdFVBNPrnptm1CwePrnptm1CweTgPrnpP101L2866SbpTgPrnpP101L2866SbpPrnptm1CweTgPrnpP101L2866Sbp

spongiform encephalopathy_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*P101L)2866Sbp/Tg(Prnp*P101L)2866Sbp

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2866, Stanley B Prusiner
  http://metadb.riken.jp/db/mgi_rdf/MGI:5491018
• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(Prnp*P101L)2866Sbp/Tg(Prnp*P101L)2866Sbp

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prnp<tm1Cwe>|Tg(Prnp*P101L)2866Sbp

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• spongiform encephalopathy
  http://purl.obolibrary.org/obo/MP_0002654

文献

http://purl.org/net/cito/citesAsAuthority

• G C. Telling, et.al., Interactions between wild-type and mutant prion proteins modulate neurodegeneration in transgenic mice., Genes & development, 1996, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/8698234