decreased circulating corticosterone level_Crh<tm2.1Maj>/Crh<tm2.1Maj>,Tg(Sim1-cre)1Lowl/?

http://metadb.riken.jp/0002665I129S4SvJaeC57BL6FVBNCrhtm21MajCrhtm21MajTgSim1cre1LowlTgSim1cre1LowlCrhtm21Maj

decreased circulating corticosterone level_Crh<tm2.1Maj>/Crh<tm2.1Maj>,Tg(Sim1-cre)1Lowl/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Bradford B Lowell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3692524
• corticotropin releasing hormone
  http://metadb.riken.jp/db/mgi_rdf/MGI:88496

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Crh<tm2.1Maj>/Crh<tm2.1Maj>,Tg(Sim1-cre)1Lowl/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Sim1-cre)1Lowl|Crh<tm2.1Maj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating corticosterone level
  http://purl.obolibrary.org/obo/MP_0002665

文献

http://purl.org/net/cito/citesAsAuthority

• R. Zhang, et.al., Loss of hypothalamic corticotropin-releasing hormone markedly reduces anxiety behaviors in mice., Molecular psychiatry, 2017, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/27595593