abnormal pancreas physiology_X/Tg(Ela-KRAS*G12D)9Eps,Tgfbr1<tm1Bopa>/Tgfbr1<+>

http://metadb.riken.jp/0002693I129S1SvImJC57BL6FVBXTgElaKRASG12D9EpsTgfbr1tm1BopaTgfbr1Tgfbr1tm1BopaTgElaKRASG12D9EpsTgfbr1

abnormal pancreas physiology_X/Tg(Ela-KRAS*G12D)9Eps,Tgfbr1<tm1Bopa>/Tgfbr1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transforming growth factor, beta receptor I
  http://metadb.riken.jp/db/mgi_rdf/MGI:98728
• transgene insertion 9, Eric P Sandgren
  http://metadb.riken.jp/db/mgi_rdf/MGI:4452518

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• X/Tg(Ela-KRAS*G12D)9Eps,Tgfbr1<tm1Bopa>/Tgfbr1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tgfbr1<tm1Bopa>|Tg(Ela-KRAS*G12D)9Eps|Tgfbr1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/SvImJ * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreas physiology
  http://purl.obolibrary.org/obo/MP_0002693

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel R. Principe, et.al., TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis., Cancer research, 2016, 76
  http://rdf.ncbi.nlm.nih.gov/pubmed/26980767