abnormal renal tubule morphology_Nf2<tm2Gth>/Nf2<tm2Gth>,Trp53<tm1Brd>/Trp53<+>,Tg(P0-Cre)2Gth/0

http://metadb.riken.jp/0002703I129P2OlaHsd129S7SvEvBrdFVBNNf2tm2GthNf2tm2GthTrp53tm1BrdTrp53TgP0Cre2Gth0Trp53Nf2tm2GthTgP0Cre2GthTrp53tm1Brd

abnormal renal tubule morphology_Nf2<tm2Gth>/Nf2<tm2Gth>,Trp53<tm1Brd>/Trp53<+>,Tg(P0-Cre)2Gth/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neurofibromin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97307
• transgene insertion 2, Gilles Thomas
  http://metadb.riken.jp/db/mgi_rdf/MGI:3047116
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf2<tm2Gth>/Nf2<tm2Gth>,Trp53<tm1Brd>/Trp53<+>,Tg(P0-Cre)2Gth/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Nf2<tm2Gth>|Tg(P0-Cre)2Gth|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal renal tubule morphology
  http://purl.obolibrary.org/obo/MP_0002703

文献

http://purl.org/net/cito/citesAsAuthority

• Els. Robanus-Maandag, et.al., Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin., Oncogene, 2004, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/15221010