abnormal renal tubule morphology_Mtor<tm1.1Seq>/Mtor<tm1.2Seq>,Tg(Nphs2-cre)1Seq/?

http://metadb.riken.jp/0002703I129S1Sv129X1SvJC57BL6SJLMtortm11SeqMtortm12SeqTgNphs2cre1SeqMtortm12SeqTgNphs2cre1SeqMtortm11Seq

abnormal renal tubule morphology_Mtor<tm1.1Seq>/Mtor<tm1.2Seq>,Tg(Nphs2-cre)1Seq/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mechanistic target of rapamycin (serine/threonine kinase)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928394
• transgene insertion 1, Susan E Quaggin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3586449

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mtor<tm1.1Seq>/Mtor<tm1.2Seq>,Tg(Nphs2-cre)1Seq/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mtor<tm1.2Seq>|Tg(Nphs2-cre)1Seq|Mtor<tm1.1Seq>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal renal tubule morphology
  http://purl.obolibrary.org/obo/MP_0002703

文献

http://purl.org/net/cito/citesAsAuthority

• Davide P. Cinà, et.al., Inhibition of MTOR disrupts autophagic flux in podocytes., Journal of the American Society of Nephrology : JASN, 2012, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/22193387